Iowa State Cyclones' forward Addy Brown (24) takes a three-point shot against Oklahoma State Cowgirls during the first quarter in the senior day women basketball at Hilton Coliseum on February. 25, 2026, in Ames, Iowa.
Iowa State Cyclones' forward Addy Brown (24) takes a three-point shot against Oklahoma State Cowgirls during the first quarter in the senior day women basketball at Hilton Coliseum on February. 25, 2026, in Ames, Iowa.
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March Madness first-round predictions, picks for every women’s game.

Looking to come out on top in your work or friends’ March Madness pool? We’ve got you covered.

The 68-team women’s tournament tips off on Wednesday, March 18, with the First Four games to determine the remaining spots in the Round of 64.

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Here are our predictions for the opening round of March Madness.

Women’s March Madness bracket predictions

Predictions for the opening round

First Four

Wednesday, March 18

Thursday, March 19

Round of 64

Friday, March 20

Saturday, March 21

Iowa, Iowa State tickets for Women’s March Madness 2026 

Cooper Worth is a service/trending reporter for the Des Moines Register. Reach him at cworth@gannett.com or follow him on X @CooperAWorth.

This article originally appeared on Des Moines Register: March Madness first-round predictions, picks for every women’s game.

Reporting by Cooper Worth, Des Moines Register / Des Moines Register

USA TODAY Network via Reuters Connect

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