The Indianapolis Colts (4-1) host the Arizona Cardinals (2-3) today at Lucas Oil Stadium in NFL Week 6 action.
The Colts are getting wide receiver Alec Pierce (concussion) back after two weeks out, but cornerback Kenny Moore II (hamstring) remains out. The Colts lost kicker Spencer Shrader (knee) for the season and Michael Badgley is the new kicker.
Several Cardinals starters have been in the injury report this week: quarterback Kyler Murray (foot), receiver Zay Jones (knee), left guard Evan Brown (hamstring), right tackle Jonah Williams (foot), defensive end Darius Robinson (pectoral), linebackers Mack Wilson (ankle) and Cody Simon (knee), and cornerbacks Will Johnson (groin) and Max Melton (hamstring).
Indianapolis Colts inactives vs. Arizona Cardinals today, Oct. 12
Tyler Goodson, Will Mallory, Adonai Mitchell, Kenny Moore II, Anthony Richardson Sr., Luke Tenuta, J.T. Tuimoloau.
Mitchell made a couple of major mistakes two weeks ago in a loss to the Los Angeles Rams, and he only played mop-up snaps in Week 5. He is a healthy scratch, as is quarterback Richardson. Riley Leonard is Daniel Jones’ backup.
Arizona Cardinals inactives today vs. Indianapolis Colts on Oct. 12
Darius Robinson, Elijah Jones, Zay Jones, Demontrey Jacobs, Josh Fryar, Xavier Weaver, Bilal Nichols.
Jacoby Brissett takes over at quarterback. He played four seasons for the Colts, and was the primary starters in the 2017 and ’19 seasons.
What time does Indianapolis Colts-Arizona Cardinals NFL game start Sunday, Oct. 12, 2025? When is Cardinals-Colts NFL football game start time?
The Indianapolis Colts-Arizona Cardinals game is at 1 p.m. ET Sunday, Oct. 12, 2025, at Lucas Oil Stadium in Indianapolis.
Where to watch Arizona Cardinals vs Indianapolis Colts game on TV Sunday, Oct. 12, 2025? How to watch NFL Week 6 football game live
TV: Fox, with Kevin Kugler (play-by-play), Daryl Johnston (analysis) and Allison Williams (sideline reporting)
Watch Colts vs. Raiders in Week 6 on Fubo (free trial)
Joel A. Erickson covers the Colts all season. Get more coverage on IndyStarTV and with the Colts Insider newsletter.
This article originally appeared on Indianapolis Star: Is Kyler Murray playing today? Arizona Cardinals vs. Indianapolis Colts inactives today in NFL Week 6
Reporting by Scott Horner, Indianapolis Star / Indianapolis Star
USA TODAY Network via Reuters Connect
