Indiana Head Coach Curt Cignetti during the Indiana versus Kennesaw State Big Ten football game at Memorial Stadium on Saturday, Sept. 6, 2025.
Indiana Head Coach Curt Cignetti during the Indiana versus Kennesaw State Big Ten football game at Memorial Stadium on Saturday, Sept. 6, 2025.
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Big Ten football expert picks and predictions for Week 3 of the college football season

It’s tradition now. Every year (and every week of the season) we have a little friendly competition among our writers for world domination when it comes to picking the Big Ten football games and some of the bigger college football contests throughout the season once conference play gets into full swing.

Though we never really know, Ohio State, Oregon, and Penn State, are getting a lot of national notoriety and were picked by media members to be the three teams contending for league superiority. You can’t count out Michigan despite last week’s loss to Oklahoma, and teams like Wisconsin, Iowa, Illinois, and Nebraska hope to also be upstarts and surprise folks.

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So, just how will Week 3 play out in the Big Ten? Our writers take turns picking all the games in the Big Ten straight up and against the spread for your wagering and reading consumption — do with it as you wish.

As a reminder, if there’s an asterisk next to the pick, that means the team will win, but not cover. If there is a tie, rather than have a cage match or old-fashioned duel, we’ll settle it with less violence and go with the tried, yet true, coin flip where George Washington has the say.

EXAMPLE: If Ohio State is favored -3.5 over Michigan:

If you think Ohio State will win outright and cover: OSU

If you think Ohio State will win, but NOT cover: OSU*

If you think Ohio State will lose: Michigan

Here are our expert picks for Week 2 as we see if what we saw during opening weekend holds true this week. But first, here are the standings so far from our writers

Standings so far

Follow Phil Harrison: 35-1 SU, 21-15 ATS

Follow MarkRussell: 34-2 SU, 19-17 ATS

Follow Yesh Ginsburg: 30-6 SU, 22-14 ATS

Follow Griffin Dreifeldt: 36-0 SU, 24-12 ATS

CONSENSUS PICK: 34-2 SU, 24-12 ATS

Indiana vs. Indiana State

Friday, Sept. 12

6:30 p.m. ET | Big Ten Network (Stream fuboTV (watch here))

Betting Line | Off

The Picks:

Phil Harrison (@PhilHarrisonBW) | Indiana

Mark Russell (@MarkRussell1975) | Indiana

Griffin Dreifaldt (@griffin_drei) | Indiana

Yesh Ginsburg (@yesh222) | Indiana

CONSENSUS PICK | Indiana

New Mexico vs. UCLA

Friday, Sept. 12

10:00 p.m. ET | Big Ten Network (Stream fuboTV (watch here))

Betting Line | UCLA -15.5

The Picks:

Phil Harrison (@PhilHarrisonBW) | UCLA

Mark Russell (@MarkRussell1975) | UCLA

Griffin Dreifaldt (@griffin_drei) | UCLA

Yesh Ginsburg (@yesh222) | UCLA*

CONSENSUS PICK | UCLA

Oregon vs. Northwestern

Saturday, Sept. 13

Noon ET | Fox (Stream fuboTV (watch here))

Betting Line | Oregon -27.5

The Picks:

Phil Harrison (@PhilHarrisonBW) | Oregon

Mark Russell (@MarkRussell1975) | Oregon

Griffin Dreifaldt (@griffin_drei) | Oregon

Yesh Ginsburg (@yesh222) | Oregon

CONSENSUS PICK: Oregon

Wisconsin at Alabama

Saturday, Sept. 13

Noon ET | ABC (Stream fuboTV (watch here))

Betting Line | Alabama -20.5

The Picks:

Phil Harrison (@PhilHarrisonBW) | Alabama

Mark Russell (@MarkRussell1975) | Alabama

Griffin Dreifaldt (@griffin_drei) | Alabama

Yesh Ginsburg (@yesh222) | Alabama*

CONSENSUS PICK | Alabama

Central Michigan at Michigan (the Connor Stalions Bowl)

Saturday, Sept. 13

Noon ET | Big Ten Network (Stream fuboTV (watch here))

Betting Line | Michigan -27.5

The Picks:

Phil Harrison (@PhilHarrisonBW) | Michigan

Mark Russell (@MarkRussell1975) | Michigan

Griffin Dreifaldt (@griffin_drei) | Michigan

Yesh Ginsburg (@yesh222) | Michigan*

CONSENSUS PICK | Michigan

Nebraska vs. Houston Christian

Saturday, Sept. 13

Noon ET | FS1 (Stream fuboTV (watch here))

Betting Line | Off

The Picks:

Phil Harrison (@PhilHarrisonBW) | Nebraska

Mark Russell (@MarkRussell1975) | Nebraska

Griffin Dreifaldt (@griffin_drei) | Nebraska

Yesh Ginsburg (@yesh222) | Nebraska

CONSENSUS PICK | Nebraska

Maryland vs. Townsend

Saturday, Sept. 13

Noon ET | Peacock

Betting Line | Off

The Picks:

Phil Harrison (@PhilHarrisonBW) | Maryland

Mark Russell (@MarkRussell1975) | Maryland

Griffin Dreifaldt (@griffin_drei) | Maryland

Yesh Ginsburg (@yesh222) | Maryland

CONSENSUS PICK | Maryland

Penn State vs. Villanova

Saturday, Sept. 13

3:30 p.m. ET | FS1 (Stream fuboTV (watch here))

Betting Line | Off

The Picks:

Phil Harrison (@PhilHarrisonBW) | Penn State

Mark Russell (@MarkRussell1975) | Penn State

Griffin Dreifaldt (@griffin_drei) | Penn State

Yesh Ginsburg (@yesh222) | Penn State

CONSENSUS PICK | Penn State

USC at Purdue

Saturday, Sept. 13

3:30 p.m. ET | CBS/Paramount+ (Stream fuboTV (watch here))

Betting Line | USC -20.5

The Picks:

Phil Harrison (@PhilHarrisonBW) | USC

Mark Russell (@MarkRussell1975) | USC

Griffin Dreifaldt (@griffin_drei) | USC

Yesh Ginsburg (@yesh222) | USC

CONSENSUS PICK | USC

Rutgers vs. Norfolk State

Saturday, Sept. 13

3:30 p.m. ET | Big Ten Network (Stream fuboTV (watch here))

Betting Line | Off

The Picks:

Phil Harrison (@PhilHarrisonBW) | Rutgers

Mark Russell (@MarkRussell1975) | Rutgers

Griffin Dreifaldt (@griffin_drei) | Rutgers

Yesh Ginsburg (@yesh222) | Rutgers

CONSENSUS PICK | Rutgers

Michigan State vs. Youngstown State

Saturday, Sept. 13

3:30 p.m. ET | Big Ten Network (Stream fuboTV (watch here))

Betting Line | Off

The Picks:

Phil Harrison (@PhilHarrisonBW) | Michigan State

Mark Russell (@MarkRussell1975) | Michigan State

Griffin Dreifaldt (@griffin_drei) | Michigan State

Yesh Ginsburg (@yesh222) | Michigan State

CONSENSUS PICK | Michigan State

Illinois vs. Western Michigan

Saturday, Sept. 13

7:00 p.m. ET | FS1 (Stream fuboTV (watch here))

Betting Line | Illinois -27.5

The Picks:

Phil Harrison (@PhilHarrisonBW) | Illinois

Mark Russell (@MarkRussell1975) | Illinois

Griffin Dreifaldt (@griffin_drei) | Illinois

Yesh Ginsburg (@yesh222) | Illinois

CONSENSUS PICK | Illinois

Ohio State vs. Ohio

Saturday, Sept. 13

7:30 p.m. ET | Peacock

Betting Line | Off

The Picks:

Phil Harrison (@PhilHarrisonBW) | Ohio State

Mark Russell (@MarkRussell1975) | Ohio State

Griffin Dreifaldt (@griffin_drei) | Ohio State

Yesh Ginsburg (@yesh222) | Ohio State

CONSENSUS PICK |

Iowa vs. UMass

Saturday, Sept. 13

7:30 p.m. ET | Big Ten Network (Stream fuboTV (watch here))

Betting Line | Iowa -35.5

The Picks:

Phil Harrison (@PhilHarrisonBW) | Iowa*

Mark Russell (@MarkRussell1975) | Iowa

Griffin Dreifaldt (@griffin_drei) | Iowa

Yesh Ginsburg (@yesh222) | Iowa

CONSENSUS PICK | Iowa

Minnesota at California

Saturday, Sept. 13

10:30 p.m. ET | ESPN (Stream fuboTV (watch here))

Bettting Line | Minnesota -2.5

The Picks:

Phil Harrison (@PhilHarrisonBW) | California

Mark Russell (@MarkRussell1975) | Minnesota

Griffin Dreifaldt (@griffin_drei) | Minnesota

Yesh Ginsburg (@yesh222) | Minnesota

CONSENSUS PICK | Minnesota

Contact/Follow us @BuckeyesWire on X (formerly Twitter) and like our page on Facebook to follow ongoing coverage of Ohio State news, notes and opinion.

This article originally appeared on Buckeyes Wire: Big Ten football expert picks and predictions for Week 3 of the college football season

Reporting by Phil Harrison, Buckeyes Wire / Buckeyes Wire

USA TODAY Network via Reuters Connect

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