Dec 28, 2025; Santa Clara, California, USA; San Francisco 49ers wide receiver Ricky Pearsall (1) celebrates in the first half against the Chicago Bears at Levi's Stadium. Mandatory Credit: Sergio Estrada-Imagn Images
Dec 28, 2025; Santa Clara, California, USA; San Francisco 49ers wide receiver Ricky Pearsall (1) celebrates in the first half against the Chicago Bears at Levi's Stadium. Mandatory Credit: Sergio Estrada-Imagn Images
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Betting odds for every San Francisco 49ers game in 2026

The San Francisco 49ers have one of the easiest schedules in the league in 2026, but they’re expected to travel nearly 40,000 miles with two international games on the docket, which will certainly make things more difficult.

After knowing who they were going to play for the last few months, San Francisco now knows when these games will take place, as the league released the 2026 schedule on Thursday.

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While there’s still plenty of time before the 49ers step on the field for the first time, let’s look at the odds for each game on the schedule (via DraftKings).

More 49ers: Game-by-game predictions for 49ers’ 2026 season: How many wins for SF?

This article originally appeared on Niners Wire: Betting odds for every San Francisco 49ers game in 2026

Reporting by Mike Masala, Niners Wire / Niners Wire

USA TODAY Network via Reuters Connect

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