Nov 1, 2025; Minneapolis, Minnesota, USA; Minnesota Golden Gophers quarterback Drake Lindsey (5) looks to throw against the Michigan State Spartans during the second half at Huntington Bank Stadium. Mandatory Credit: Matt Krohn-Imagn Images
Nov 1, 2025; Minneapolis, Minnesota, USA; Minnesota Golden Gophers quarterback Drake Lindsey (5) looks to throw against the Michigan State Spartans during the second half at Huntington Bank Stadium. Mandatory Credit: Matt Krohn-Imagn Images
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Spartans Wire Picks: Our predictions for every Week 12 Big Ten game

We are on the home stretch of the college football season, with the Spartans only having three games to go on the year.

Michigan State is set to host Penn State for its final home game of the season on Saturday afternoon. This is just one game on a full slate of Big Ten action this week.

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The Spartans Wire staff is back again this week to provide picks against the spread for each Big Ten game. Before turning our focus to this week, here are the current standings from our weekly picks:

Check out our picks for this week’s upcoming games — odds are courtesy of FanDuel.

Minnesota at Oregon (minus-24 1/2)

Our Picks

Robert Bondy – Minnesota

Cory Linsner – Minnesota

Andrew Brewster – Minnesota

Wisconsin at Indiana (minus-29 1/2)

Our Picks

Robert Bondy – Wisconsin

Cory Linsner – Wisconsin

Andrew Brewster – Indiana

Michigan (minus-11 1/2) at Northwestern

Our Picks

Robert Bondy – Northwestern

Cory Linsner – Michigan

Andrew Brewster – Northwestern

Maryland at Illinois (minus-15 1/2)

Our Picks

Robert Bondy – Illinois

Cory Linsner – Illinois

Andrew Brewster – Illinois

Iowa at USC (minus-6 1/2)

Our Picks

Robert Bondy – USC

Cory Linsner – Iowa

Andrew Brewster – USC

Purdue at Washington (minus-16 1/2)

Our Picks

Robert Bondy – Washington

Cory Linsner – Purdue

Andrew Brewster – Washington

UCLA at Ohio State (minus-32 1/2)

Our Picks

Robert Bondy – Ohio State

Cory Linsner – UCLA

Andrew Brewster – UCLA

Penn State (minus-7 1/2) at Michigan State

Our Picks

Robert Bondy – Michigan State

Cory Linsner – Penn State

Andrew Brewster – Michigan State

Contact/Follow us @The SpartansWire on X (formerly Twitter) and like our page on Facebook to follow ongoing coverage of Michigan State news, notes and opinion. You can also follow Robert Bondy on X @RobertBondy5.

This article originally appeared on Spartans Wire: Spartans Wire Picks: Our predictions for every Week 12 Big Ten game

Reporting by Robert Bondy, Spartans Wire / Spartans Wire

USA TODAY Network via Reuters Connect

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