Iowa football hosts Michigan State on senior day inside Kinnick Stadium on Saturday, Nov. 22. FS1 will televise the 2:30 p.m. CT game.
The Hawkeyes (6-4, 4-3 Big Ten Conference) are trying to end their first two-game regular-season losing streak since 2022, coming on the heels of consecutive close defeats to ranked teams.

Michigan State (3-7, 0-7) started 3-0 before losing seven consecutive Big Ten contests. Michigan State suffered a 28-10 home loss to Penn State last time out.
Here are the betting odds and what experts predict for the game:
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Iowa vs. Michigan State odds, money line, over/under
Odds courtesy of BetMGM as of Friday evening.
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Iowa vs. Michigan State predictions, picks for college football Week 13
Chad Leistikow, Hawkeyes columnist: “Iowa 34, Michigan State 13 … Iowa does indeed pass for 200 and rush for 200 in a get-well rout on senior day. A running back will spring a rush of 30-plus yards for the first time since the season opener, and the defense will finish plus-2 in turnovers.” – (full prediction column)
This article originally appeared on Des Moines Register: Iowa vs Michigan State predictions, picks, odds for college football
Reporting by Gus Martin, Des Moines Register / Des Moines Register
USA TODAY Network via Reuters Connect
